The CBI are called to the murder of Xander Harrington, a wealthy media corporation’s CEO. The investigation leads to the Visualize Self-Realization Center, a cult-like religious group.

After the murder of ADA Kelly Flower, Jane quickly identifies her killer. The CBI team find out he may be a serial killer but have no proof for it. When they discover him to be a hitman, they set up an undercover operation.

Jane and the team discover a murder scene along with a woman covered in blood and suffering from amnesia, so now it is up to Jane to help her get her memory back. Meanwhile, Hightower addresses the issue of the romantic relationship between Rigsby and Van Pelt.

Jane and the team investigate the murder of a tutor and find a mysterious little red box near the body. Meanwhile, Lisbon is worried when Madeleine Hightower takes charge of the CBI.

After being poisoned with the toxin she was working on, bioweapons researcher Dr. Alicia Seberg asks Jane and the CBI to find her killer.

Jane and the team are asked to investigate the murder of Jeffrey Barge, a prominent chef, who was poisoned right at a best chef challenge.

Jane tags along with Cho who helps the police with a murder investigation with the victim being a fellow gang member from his early days, who also used to be his best friend.

When the body of Liselle Douglas, a beautiful, young car salesman, is found stuffed in the trunk of a high-end vehicle at an elite car dealership, Jane and the CBI are asked to investigate.

The CBI is assigned to investigate the murder of the mayor’s media liaison, a case that draws the attention of the media. Reporter Mike Brewster is assigned to watch the team’s work and take some interviews with the staff.

The CBI team investigate the double homicide of a couple murdered on their way to his high school reunion. Jane soon finds a link to an old high school prank.

The CBI team investigate the murder of a former professional baseball player, who has started his own baseball talent scouting and training facility for young up-and-coming baseball talents. During the investigation, Jane is knocked out by a baseball and flashes back to his past as a stage performer.

The CBI team investigates the murder of a wealthy jeweler who was killed during a robbery. However, the investigation takes an interesting turn for the worse when the prime suspect is found dead.

A fatal shooting inside the walls of CBI Headquarters puts Jane, Lisbon and the rest of the team back on the trail of Red John.

When two cases overlap, Minelli orders Bosco’s and Lisbon’s units to team up for the investigation of a kidnapping crime. Soon, the two different procedural approaches start to collide and cause tensions among the team members.

Bosco arrests Jane during a murder investigation and puts him behind bars for spying on Bosco’s team and the Red John case. However, even in jail Jane manages to help Lisbon’s team with the ongoing investigation.

The CBI are called to Beckworth Mansion, where a murdered body was found. The local deputy sheriff believes that Walter Beckworth’s ghost haunts the mansion and killed the new owner, so the investigation is accompanied by a discussion about the existence of ghosts.

The CBI investigate the murder of a powerful and under-handed criminal attorney whose only client was one of California’s most notorious motorcycle gangs.

After they receive an anonymous tip, the CBI team finds the dead body of a child molester Lisbon had arrested years ago together with Sam Bosco, now Lisbon quickly turns out to be the prime suspect.

The CBI are called in to investigate the death of Kristin Marley, a prominent state senator’s aide, who was rumoured to have had an affair with the senator’s husband. Meanwhile, Jane attempts to figure out what new information Sam Bosco and his team have discovered on the Red John case.

Minelli decides to assign the Red John case to Sam Bosco, when he thinks that Lisbon and Jane are too close to the case. Jane thereafter decides to solve one more case, then leave the CBI. They investigate the murder of a woman who is found suffocated after being accused of stealing a million dollars...